CD4+CD28null T lymphocytes are expanded in young women with polycystic ovary syndrome

Rosanna Apa, Antonio Lanzone, Giovanna Liuzzo, Filippo Crea, Giampaolo Niccoli, Cristina Spaziani, Francesca Sagnella, Nicola Cosentino, Francesca Moro, Daniela Martinez, Andrea Morciano, Marco Baca', Vincenzo Pazzano, Maria Francesca Gangale, Anna Tropea

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

19 Citazioni (Scopus)

Abstract

Women affected by polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. We demonstrated that women with PCOS showed an expansion of CD4+CD28null T cells, an aggressive population of T lymphocytes that has been recently associated with recurrent coronary instability and type 2 diabetes mellitus. This sheds new light on possible mechanisms responsible for the higher rate of cardiovascular disease among women with PCOS.
Lingua originaleEnglish
pagine (da-a)2651-2654
Numero di pagine4
RivistaFertility and Sterility
Volume2011
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Inflammation
  • hyperinsulinemia

Fingerprint

Entra nei temi di ricerca di 'CD4+CD28null T lymphocytes are expanded in young women with polycystic ovary syndrome'. Insieme formano una fingerprint unica.

Cita questo