Cardiovascular disease and SARS-CoV-2: The role of host immune response versus direct viral injury

Piergiorgio Bruno, Andrea Flex, Federico Biscetti, Elisabetta Nardella, Andrea Leonardo Cecchini, Raffaele Landolfi, M. M. Rando

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

The 2019 novel coronavirus [2019-nCoV], which started to spread from December 2019 onwards, caused a global pandemic. Besides being responsible for the severe acute respiratory syndrome 2 [SARS-CoV-2], the virus can affect other organs causing various symptoms. A close relationship between SARS-CoV-2 and the cardiovascular system has been shown, demonstrating an epidemiological linkage between SARS-CoV-2 and cardiac injury. There are emerging data regarding possible direct myocardial damage by 2019-nCoV. In this review, the most important available evidences will be discussed to clarify the precise mechanisms of cardiovascular injury in SARS-CoV-2 patients, even if further researches are needed.
Lingua originaleEnglish
pagine (da-a)1-14
Numero di pagine14
RivistaInternational Journal of Molecular Sciences
Volume21
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • Cardiovascular diseases
  • SARS-CoV-2
  • Animals
  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections
  • Humans
  • Pandemics
  • Pneumonia, Viral
  • Cardiovascular Diseases

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