Cardiovascular disease and SARS-CoV-2: The role of host immune response versus direct viral injury

Federico Biscetti*, M. M. Rando, E. Nardella, A. L. Cecchini, P. Bruno, R. Landolfi, Andrea Flex

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo

1 Citazioni (Scopus)

Abstract

The 2019 novel coronavirus [2019-nCoV], which started to spread from December 2019 onwards, caused a global pandemic. Besides being responsible for the severe acute respiratory syndrome 2 [SARS-CoV-2], the virus can affect other organs causing various symptoms. A close relationship between SARS-CoV-2 and the cardiovascular system has been shown, demonstrating an epidemiological linkage between SARS-CoV-2 and cardiac injury. There are emerging data regarding possible direct myocardial damage by 2019-nCoV. In this review, the most important available evidences will be discussed to clarify the precise mechanisms of cardiovascular injury in SARS-CoV-2 patients, even if further researches are needed.
Lingua originaleInglese
pagine (da-a)1-14
Numero di pagine14
RivistaInternational Journal of Molecular Sciences
Volume21
Numero di pubblicazione21
DOI
Stato di pubblicazionePubblicato - 2020

All Science Journal Classification (ASJC) codes

  • Catalisi
  • Biologia Molecolare
  • Spettroscopia
  • Informatica Applicata
  • Chimica Fisica e Teorica
  • Chimica Organica
  • Chimica Inorganica

Keywords

  • Animals
  • Betacoronavirus
  • COVID-19
  • Cardiovascular Diseases
  • Cardiovascular diseases
  • Coronavirus Infections
  • Humans
  • Pandemics
  • Pneumonia
  • SARS-CoV-2
  • Viral

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