Cardiac metastasis from renal cell carcinoma successfully treated with pazopanib: impact of TKIs' antiangiogenic activity.

Alessandra Cassano, Giovanni Schinzari, Santa Monterisi, Diego Signorelli, Maria Silvia Cona, Francesco Danza, Carlo Antonio Barone

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

Cardiac metastasis from renal cell carcinoma, especially without neoplastic thrombosis of the vena cava, is extremely rare. The prognosis of patients with metastatic renal cell carcinoma has been radically influenced by the introduction of tyrosine kinase inhibitors, but very few reports in the literature have described their activity in heart metastasis. We report the case of a woman with a left ventricle metastasis from kidney cancer without renal vein involvement, who was treated with pazopanib. The patient achieved a prolonged partial response, with clear signs of metastasis devascularization and a favorable toxicity profile.
Lingua originaleEnglish
pagine (da-a)298-300
Numero di pagine3
RivistaTumori
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • cardiac metastasis
  • metastasi cardiache
  • pazopanib
  • renal tumor
  • tumore renale

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