TY - JOUR
T1 - Cardiac Magnetic Resonance Features of Fabry Disease: From Early Diagnosis to Prognostic Stratification
AU - Camporeale, Antonia
AU - Diano, Alberto
AU - Tondi, Lara
AU - Pica, Silvia
AU - Pasqualin, Giulia
AU - Ciabatti, Michele
AU - Graziani, Francesca
AU - Pieroni, Maurizio
AU - Lombardi, Massimo
PY - 2022
Y1 - 2022
N2 - In the past few years, the wide application of cardiac magnetic resonance (CMR) significantly changed the approach to the study of cardiac involvement in Fabry Disease (FD). The possibility to perform non-invasive tissue characterization, including new sequences such as T1/T2 mapping, offered a powerful tool for differential diagnosis with other forms of left ventricular hypertrophy. In patients with confirmed diagnosis of FD, CMR is the most sensitive non-invasive technique for early detection of cardiac involvement and it provides new insight into the evolution of cardiac damage, including gender-specific features. Finally, CMR multiparametric detection of subtle changes in cardiac morphology, function and tissue composition is potentially useful for monitoring the efficacy of specific treatment over time. This paper aims to provide a comprehensive review of current knowledge regarding the application of CMR in FD cardiac involvement and its clinical implication.
AB - In the past few years, the wide application of cardiac magnetic resonance (CMR) significantly changed the approach to the study of cardiac involvement in Fabry Disease (FD). The possibility to perform non-invasive tissue characterization, including new sequences such as T1/T2 mapping, offered a powerful tool for differential diagnosis with other forms of left ventricular hypertrophy. In patients with confirmed diagnosis of FD, CMR is the most sensitive non-invasive technique for early detection of cardiac involvement and it provides new insight into the evolution of cardiac damage, including gender-specific features. Finally, CMR multiparametric detection of subtle changes in cardiac morphology, function and tissue composition is potentially useful for monitoring the efficacy of specific treatment over time. This paper aims to provide a comprehensive review of current knowledge regarding the application of CMR in FD cardiac involvement and its clinical implication.
KW - fabry disease
KW - T1 mapping
KW - late gadolinium enhancement
KW - cardiac magnetic resonance
KW - fabry disease
KW - T1 mapping
KW - late gadolinium enhancement
KW - cardiac magnetic resonance
UR - http://hdl.handle.net/10807/227312
U2 - 10.31083/j.rcm2305177
DO - 10.31083/j.rcm2305177
M3 - Article
SN - 1530-6550
VL - 23
SP - 177-N/A
JO - Reviews in Cardiovascular Medicine
JF - Reviews in Cardiovascular Medicine
ER -