Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

Roberto Pallini, Maurizio Martini, Luigi Maria Larocca, Giulio Maira, Lucia Ricci Vitiani, Giuseppe Luigi Banna, Michele Signore, Dario Lombardi, Matilde Todaro, Giorgio Stassi, Ruggero De Maria

Risultato della ricerca: Contributo in rivistaArticolo in rivista

266 Citazioni (Scopus)

Abstract

Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients.
Lingua originaleEnglish
pagine (da-a)8205-8212
Numero di pagine8
RivistaClinical Cancer Research
Volume14
DOI
Stato di pubblicazionePubblicato - 2008

Keywords

  • Adult
  • Aged
  • Antigens, CD
  • Brain Neoplasms
  • Female
  • Glioblastoma
  • Glycoproteins
  • Humans
  • Ki-67 Antigen
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Neoplastic Stem Cells
  • Peptides
  • Prospective Studies

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