Cancer Predisposition Syndromes Associated With Pediatric High-Grade Gliomas

G. Ceglie; Baldo G. Del; E. Agolini; M. Rinelli; A. Cacchione; Bufalo F. Del; M. Vinci; R. Carta; L. Boccuto; E. Miele; A. Mastronuzzi; Franco Locatelli; A. Carai

doi:10.3389/fped.2020.561487

Cancer Predisposition Syndromes Associated With Pediatric High-Grade Gliomas

G. Ceglie, Baldo G. Del, E. Agolini, M. Rinelli, A. Cacchione, Bufalo F. Del, M. Vinci, R. Carta, L. Boccuto, E. Miele, A. Mastronuzzi^*, Franco Locatelli, A. Carai

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

Pediatric High-Grade Gliomas (pHGG) are among the deadliest childhood brain tumors and can be associated with an underlying cancer predisposing syndrome. The thorough understanding of these syndromes can aid the clinician in their prompt recognition, leading to an informed genetic counseling for families and to a wider understanding of a specific genetic landscape of the tumor for target therapies. In this review, we summarize the main pHGG-associated cancer predisposing conditions, providing a guide for suspecting these syndromes and referring for genetic counseling.

Lingua originale	Inglese
pagine (da-a)	1-10
Numero di pagine	10
Rivista	Frontiers in Pediatrics
Volume	8
Numero di pubblicazione	8
DOI	https://doi.org/10.3389/fped.2020.561487
Stato di pubblicazione	Pubblicato - 2020

All Science Journal Classification (ASJC) codes

Pediatria, Perinatologia e Salute del Bambino

Keywords

brain tumors
cancer predisposition
genetics of cancer
high grade gliomas
pediatric neuro- oncology

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

Accesso al documento

10.3389/fped.2020.561487

Altri file e collegamenti

Cita questo

@article{8bc0aeb4e39442acb4f9b9d68c327356,

title = "Cancer Predisposition Syndromes Associated With Pediatric High-Grade Gliomas",

abstract = "Pediatric High-Grade Gliomas (pHGG) are among the deadliest childhood brain tumors and can be associated with an underlying cancer predisposing syndrome. The thorough understanding of these syndromes can aid the clinician in their prompt recognition, leading to an informed genetic counseling for families and to a wider understanding of a specific genetic landscape of the tumor for target therapies. In this review, we summarize the main pHGG-associated cancer predisposing conditions, providing a guide for suspecting these syndromes and referring for genetic counseling.",

keywords = "brain tumors, cancer predisposition, genetics of cancer, high grade gliomas, pediatric neuro- oncology, brain tumors, cancer predisposition, genetics of cancer, high grade gliomas, pediatric neuro- oncology",

author = "G. Ceglie and Del, \{Baldo G.\} and E. Agolini and M. Rinelli and A. Cacchione and Del, \{Bufalo F.\} and M. Vinci and R. Carta and L. Boccuto and E. Miele and A. Mastronuzzi and Franco Locatelli and A. Carai",

year = "2020",

doi = "10.3389/fped.2020.561487",

language = "English",

volume = "8",

pages = "1--10",

journal = "Frontiers in Pediatrics",

issn = "2296-2360",

publisher = "Frontiers Media SA",

number = "8",

}

TY - JOUR

T1 - Cancer Predisposition Syndromes Associated With Pediatric High-Grade Gliomas

AU - Ceglie, G.

AU - Del, Baldo G.

AU - Agolini, E.

AU - Rinelli, M.

AU - Cacchione, A.

AU - Del, Bufalo F.

AU - Vinci, M.

AU - Carta, R.

AU - Boccuto, L.

AU - Miele, E.

AU - Mastronuzzi, A.

AU - Locatelli, Franco

AU - Carai, A.

PY - 2020

Y1 - 2020

N2 - Pediatric High-Grade Gliomas (pHGG) are among the deadliest childhood brain tumors and can be associated with an underlying cancer predisposing syndrome. The thorough understanding of these syndromes can aid the clinician in their prompt recognition, leading to an informed genetic counseling for families and to a wider understanding of a specific genetic landscape of the tumor for target therapies. In this review, we summarize the main pHGG-associated cancer predisposing conditions, providing a guide for suspecting these syndromes and referring for genetic counseling.

AB - Pediatric High-Grade Gliomas (pHGG) are among the deadliest childhood brain tumors and can be associated with an underlying cancer predisposing syndrome. The thorough understanding of these syndromes can aid the clinician in their prompt recognition, leading to an informed genetic counseling for families and to a wider understanding of a specific genetic landscape of the tumor for target therapies. In this review, we summarize the main pHGG-associated cancer predisposing conditions, providing a guide for suspecting these syndromes and referring for genetic counseling.

KW - brain tumors

KW - cancer predisposition

KW - genetics of cancer

KW - high grade gliomas

KW - pediatric neuro- oncology

KW - brain tumors

KW - cancer predisposition

KW - genetics of cancer

KW - high grade gliomas

KW - pediatric neuro- oncology

UR - https://publicatt.unicatt.it/handle/10807/229463

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85096784802&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85096784802&origin=inward

U2 - 10.3389/fped.2020.561487

DO - 10.3389/fped.2020.561487

M3 - Article

SN - 2296-2360

VL - 8

SP - 1

EP - 10

JO - Frontiers in Pediatrics

JF - Frontiers in Pediatrics

IS - 8

ER -

Cancer Predisposition Syndromes Associated With Pediatric High-Grade Gliomas

Abstract

All Science Journal Classification (ASJC) codes

Keywords

OSS delle Nazioni Unite

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo