TY - JOUR
T1 - CABG for patients with heart dysfunction: When and why to refuse surgery
AU - Bruno, Piergiorgio
AU - Iafrancesco, Mauro
AU - Massetti, Massimo
PY - 2018
Y1 - 2018
N2 - Surgical myocardial revascularization in patients with reduced left ventricular function has been a matter of debate for decades. A recently-published 10-year extension follow-up of the STICH trial has conclusively demonstrated the benefit of surgical myocardial revascularization in patients with significant coronary artery disease and low left ventricular ejection fraction. However, patient selection for surgery remains challenging, and so does the decision to perform percutaneous rather than surgical revascularization in this class of patients. New evidence helped to clarify the role of preoperative patients' characteristics as risk factors for surgery and to identify those patients who may benefit the most from surgery. Focus of this review is to review epidemiology and results of observational and investigational studies on revascularization in patients with reduced left ventricular function with a particular emphasis on relative indication of coronary artery bypass grafting and percutaneous coronary intervention.
AB - Surgical myocardial revascularization in patients with reduced left ventricular function has been a matter of debate for decades. A recently-published 10-year extension follow-up of the STICH trial has conclusively demonstrated the benefit of surgical myocardial revascularization in patients with significant coronary artery disease and low left ventricular ejection fraction. However, patient selection for surgery remains challenging, and so does the decision to perform percutaneous rather than surgical revascularization in this class of patients. New evidence helped to clarify the role of preoperative patients' characteristics as risk factors for surgery and to identify those patients who may benefit the most from surgery. Focus of this review is to review epidemiology and results of observational and investigational studies on revascularization in patients with reduced left ventricular function with a particular emphasis on relative indication of coronary artery bypass grafting and percutaneous coronary intervention.
KW - Cardiology and Cardiovascular Medicine
KW - Coronary Artery Bypass
KW - Coronary Artery Disease
KW - Coronary artery bypass
KW - Coronary artery disease
KW - Humans
KW - Myocardial Revascularization
KW - Patient Selection
KW - Percutaneous Coronary Intervention
KW - Percutaneous coronary intervention
KW - Risk Factors
KW - Ventricular Dysfunction, Left
KW - Ventricular Function, Left
KW - Ventricular dysfunction
KW - Cardiology and Cardiovascular Medicine
KW - Coronary Artery Bypass
KW - Coronary Artery Disease
KW - Coronary artery bypass
KW - Coronary artery disease
KW - Humans
KW - Myocardial Revascularization
KW - Patient Selection
KW - Percutaneous Coronary Intervention
KW - Percutaneous coronary intervention
KW - Risk Factors
KW - Ventricular Dysfunction, Left
KW - Ventricular Function, Left
KW - Ventricular dysfunction
UR - http://hdl.handle.net/10807/130585
UR - https://www.minervamedica.it/en/getpdf/tzwo%252bpdxblikx6fomdwqpk%252bznmkftha65ccpfdrjszn9cwonw%252fwjlrdvkoesk41gg06gcxtg0ezprbts%252fsk8eq%253d%253d/r05y2018n05a0551.pdf
U2 - 10.23736/S0026-4725.18.04711-4
DO - 10.23736/S0026-4725.18.04711-4
M3 - Article
SN - 0026-4725
VL - 66
SP - 551
EP - 561
JO - Minerva Cardioangiologica
JF - Minerva Cardioangiologica
ER -