Fifty preterm babies were randomly assigned to a group given oral bucolome (30 mg/kg per day for 5 days) and a control group. Serum bilirubin levels of the treated infants from day 4 onwards were consistently lower than those of the control infants. 3 of the 25 control infants (but none of the 25 treated infants) had bilirubin levels greater than 18 mg/100 ml (308 mumol/l) and required exchange transfusion. No sedation or drowsiness was observed in the infants given bucolome, and though the drug caused some vomiting, weight gains were unaffected.
|Numero di pagine||2|
|Rivista||Archives of Disease in Childhood|
|Stato di pubblicazione||Pubblicato - 1977|
- Clinical Trials as Topic
- Infant, Newborn
- Infant, Premature, Diseases
- Jaundice, Neonatal