Bucolome in prevention of hyperbilirubinaemia in preterm infants

Giuseppe Segni, Giancarlo Polidori, Costantino Romagnoli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

9 Citazioni (Scopus)


Fifty preterm babies were randomly assigned to a group given oral bucolome (30 mg/kg per day for 5 days) and a control group. Serum bilirubin levels of the treated infants from day 4 onwards were consistently lower than those of the control infants. 3 of the 25 control infants (but none of the 25 treated infants) had bilirubin levels greater than 18 mg/100 ml (308 mumol/l) and required exchange transfusion. No sedation or drowsiness was observed in the infants given bucolome, and though the drug caused some vomiting, weight gains were unaffected.
Lingua originaleEnglish
pagine (da-a)549-550
Numero di pagine2
RivistaArchives of Disease in Childhood
Stato di pubblicazionePubblicato - 1977


  • Barbiturates
  • Clinical Trials as Topic
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases
  • Jaundice, Neonatal
  • Male


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