Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Cristiana Ercolani; Caterina Marchiò; Anna Di Benedetto; Alessandra Fabi; Letizia Perracchio; Patrizia Vici; Francesca Sperati; Simonetta Buglioni; Vincenzo Arena; Edoardo Pescarmona; Anna Sapino Irene Terrenato; Marcella Mottolese

doi:10.1186/s13046-017-0613-2

Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Cristiana Ercolani
, Caterina Marchiò
, Anna Di Benedetto
, Alessandra Fabi
, Letizia Perracchio
, Patrizia Vici
, Francesca Sperati
, Simonetta Buglioni
, Vincenzo Arena
, Edoardo Pescarmona
, Anna Sapino Irene Terrenato
, Marcella Mottolese^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

Lingua originale	Inglese
pagine (da-a)	143-153
Numero di pagine	11
Rivista	Journal of Experimental and Clinical Cancer Research
Volume	36
Numero di pubblicazione	1
DOI	https://doi.org/10.1186/s13046-017-0613-2
Stato di pubblicazione	Pubblicato - 2017

All Science Journal Classification (ASJC) codes

Oncologia
Ricerca sul Cancro

Keywords

Amplification
HER2

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

Accesso al documento

10.1186/s13046-017-0613-2

Altri file e collegamenti

Cita questo

Ercolani, C., Marchiò, C., Benedetto, A. D., Fabi, A., Perracchio, L., Vici, P., Sperati, F., Buglioni, S., Arena, V., Pescarmona, E., Terrenato, A. S. I., & Mottolese, M. (2017). Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification. Journal of Experimental and Clinical Cancer Research, 36(1), 143-153. https://doi.org/10.1186/s13046-017-0613-2

@article{bfb2289925f04071a930784e213c1ac8,

title = "Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification",

abstract = "This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.",

keywords = "Amplification, HER2, Amplification, HER2",

author = "Cristiana Ercolani and Caterina Marchi{\`o} and Benedetto, \{Anna Di\} and Alessandra Fabi and Letizia Perracchio and Patrizia Vici and Francesca Sperati and Simonetta Buglioni and Vincenzo Arena and Edoardo Pescarmona and Terrenato, \{Anna Sapino Irene\} and Marcella Mottolese",

year = "2017",

doi = "10.1186/s13046-017-0613-2",

language = "English",

volume = "36",

pages = "143--153",

journal = "Journal of Experimental and Clinical Cancer Research",

issn = "0392-9078",

publisher = "BioMed Central",

number = "1",

}

Ercolani, C, Marchiò, C, Benedetto, AD, Fabi, A, Perracchio, L, Vici, P, Sperati, F, Buglioni, S, Arena, V, Pescarmona, E, Terrenato, ASI & Mottolese, M 2017, 'Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification', Journal of Experimental and Clinical Cancer Research, vol. 36, n. 1, pagg. 143-153. https://doi.org/10.1186/s13046-017-0613-2

TY - JOUR

T1 - Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

AU - Ercolani, Cristiana

AU - Marchiò, Caterina

AU - Benedetto, Anna Di

AU - Fabi, Alessandra

AU - Perracchio, Letizia

AU - Vici, Patrizia

AU - Sperati, Francesca

AU - Buglioni, Simonetta

AU - Arena, Vincenzo

AU - Pescarmona, Edoardo

AU - Terrenato, Anna Sapino Irene

AU - Mottolese, Marcella

PY - 2017

Y1 - 2017

N2 - This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

AB - This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

KW - Amplification

KW - HER2

KW - Amplification

KW - HER2

UR - https://publicatt.unicatt.it/handle/10807/153758

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85031318162&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85031318162&origin=inward

U2 - 10.1186/s13046-017-0613-2

DO - 10.1186/s13046-017-0613-2

M3 - Article

SN - 0392-9078

VL - 36

SP - 143

EP - 153

JO - Journal of Experimental and Clinical Cancer Research

JF - Journal of Experimental and Clinical Cancer Research

IS - 1

ER -

Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Abstract

All Science Journal Classification (ASJC) codes

Keywords

OSS delle Nazioni Unite

Accesso al documento

Altri file e collegamenti

Fingerprint

Cita questo