Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Vincenzo Arena

doi:10.1186/s13046-017-0613-2

Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

Lingua originale	English
pagine (da-a)	143-153
Numero di pagine	11
Rivista	JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume	36
DOI	https://doi.org/10.1186/s13046-017-0613-2
Stato di pubblicazione	Pubblicato - 2017

Keywords

HER2, Amplification

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10.1186/s13046-017-0613-2

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abstract = "This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.",

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author = "Vincenzo Arena",

year = "2017",

doi = "10.1186/s13046-017-0613-2",

language = "English",

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AU - Arena, Vincenzo

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N2 - This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

AB - This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signals/nucleus (s/n) ranging between 4.0 and 5.9 by in situ hybridization.

KW - HER2, Amplification

UR - http://hdl.handle.net/10807/153758

U2 - 10.1186/s13046-017-0613-2

DO - 10.1186/s13046-017-0613-2

M3 - Article

SN - 0392-9078

VL - 36

SP - 143

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JO - JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

JF - JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ER -

Breast Carcinomas With Low Amplified/Equivocal HER2 by Ish: Potential Supporting Role of Multiplex Ligation-Dependent Probe Amplification

Abstract

Keywords

OSS delle Nazioni Unite

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