Breakthrough invasive fungal diseases in acute myeloid leukemia patients receiving mould active triazole primary prophylaxis after intensive chemotherapy: An Italian consensus agreement on definitions and management

Corrado Girmenia, Alessandro Busca, Anna Candoni, Simone Cesaro, Mario Luppi, Anna Maria Nosari, Livio Pagano, Giuseppe Rossi, Adriano Venditti, Franco Aversa

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

In the attempt to establish definitions and provide shared approaches to breakthrough invasive fungal diseases (br-IFD) in acute myeloid leukemia (AML) patients submitted to intensive chemotherapy and receiving triazoles as mould active primary antifungal prophylaxis (MA-PAP), literature on br-IFD in AML patients receiving triazoles MA-PAP was reviewed and a Consensus Development Conference Project was convened. The following four candidate key-questions were generated and formed the set of questions of the present document: "definition of br-IFD," "diagnostic strategy during MA-PAP to detect br-IFD," "possible causes of MA-PAP failure," "management of br-IFD."
Lingua originaleEnglish
pagine (da-a)S127-S137-S137
Numero di pagine11
RivistaMedical Mycology
Volume57
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • acute myeloid leukemia
  • antifungal prophylaxis
  • breakthrough fungal infections
  • triazoles

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