[Bone resorption and cytokines: the role of IL-1 beta, TNF and lymphotoxin]

A. Piattelli, P. Trisi, A. D'Addona, Antonio D'Addona

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are soluble factors that play a pivotal role in acute and chronic inflammation. TNF is a 17 Kda protein mainly released by monocytes and macrophages and is a common mediator of toxic shock, cachexia and tumor necrosis. IL-1 was first described as a lymphocyte activating factor and it was then discovered that IL-1 has a number of other biological activities and that there are at least two major types of IL-1 (alpha and beta) which bind to the same receptor. Recently it has been shown that TNF and IL-1 beta have an important role in bone resorption
Titolo tradotto del contributo[Autom. eng. transl.] [Bone resorption and cytokines: the role of IL-1 beta, TNF and lymphotoxin]
Lingua originaleItalian
pagine (da-a)447-451
Numero di pagine5
RivistaMinerva Stomatologica
Volume39
Stato di pubblicazionePubblicato - 1990

Keywords

  • Bone Resorption
  • Humans
  • Inflammation
  • Interleukin-1
  • Lymphotoxin-alpha
  • Solubility
  • Tumor Necrosis Factor-alpha

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