Behavioral and personality features in patients with lateralized Parkinson's disease

Alberto Albanese, Sylvie Piacentini, Luigi Michele Antonio Romito, S. Piacentini, R. Versaci, L. Romito, F. Ferré

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

10 Citazioni (Scopus)

Abstract

Background: Dopamine neurotransmission plays a key role in several brain activities, including motor, cognitive, and behavioral functions. Parkinson's disease (PD) typically begins with asymmetrical motor features related to asymmetrical dopamine denervation. This study was designed to examine whether distinct cognitive, behavioral, and personality features are related to this asymmetry. Methods: Fifty-six patients with mild PD and lateralized motor features were grouped according to dominant side of motor features and evaluated using a neuropsychological assessment focused on attention and executive functions, impulse control disorders, and personality inventory. Results: There were no differences in neuropsychological functions between patients with right and left lateralized PD, but differences occurred in personality features. Patients with motor impairment predominant on the left-hand side had prevalence of hypomania and conversion profile. Conclusions: This study suggests that side dominance of dopaminergic denervation may be related to personality features in patients with PD that could influence behavioral aspects.
Lingua originaleEnglish
pagine (da-a)772-777
Numero di pagine6
RivistaEUROPEAN JOURNAL OF NEUROLOGY
Volume18
Stato di pubblicazionePubblicato - 2011

Keywords

  • Behavior
  • parkinson

Fingerprint

Entra nei temi di ricerca di 'Behavioral and personality features in patients with lateralized Parkinson's disease'. Insieme formano una fingerprint unica.

Cita questo