BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia

Gianfranco Spalletta, Ilaria Spoletini, Pietro Bria, Giovanni Martinotti, Dw Morris, F Angelucci, Ia Rubino, A Siracusano, G Bonaviri, S Bernardini, C Caltagirone, P Bossù, G Donohoe, M Gill, Ap Corvin

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

58 Citazioni (Scopus)

Abstract

Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.
Lingua originaleEnglish
pagine (da-a)311-313
Numero di pagine3
RivistaEuropean psychiatry : the journal of the Association of European Psychiatrists
Volume25
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adult
  • Aggression
  • Brain-Derived Neurotrophic Factor
  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease
  • Humans
  • Male
  • Methionine
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Schizophrenia
  • Schizophrenic Psychology
  • Valine

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