Abstract

Background A careful endoscopic surveillance of Barrett's oesophagus is warranted to prevent esophageal cancer. Aim To identify the preferred location of non-circumferential Barrett's oesophagus and associated dysplasia within the esophageal circumference. Methods We retrospectively reviewed a prospectively maintained database of patients with non-circumferential lesions. The location of metaplastic lesions and dysplastic lesions within the esophageal circumference was identified as on a clock face, and their distribution in the 4 quadrants was compared. Results Of overall 443 patients with Barrett's oesophagus, 192 (43%) were eligible for our study. Multiple lesions were diagnosed in 110 (57%) of them, for a total amount of 352 metaplastic areas. Barrett's oesophagus lesions were located significantly more in the posterior wall of the oesophagus (38.4%), rather than in the right wall (28.8%), the anterior wall (22.6%), or the left wall (10.2%) (P < 0.0001). Among all metaplastic lesions, 28 were associated with dysplasia (7.9%), and one with adenocarcinoma (0.3%). Dysplastic lesions were significantly more common in the posterior wall (39.3%) than, respectively, in the anterior wall (35.8%), the right wall (21.4%) or the left wall (3.5%) (P = 0.03). Conclusion Our results show that the posterior wall of the oesophagus is the preferential location of both Barrett's oesophagus and associated dysplasia.
Lingua originaleEnglish
pagine (da-a)1043-1047
Numero di pagine5
RivistaDIGESTIVE AND LIVER DISEASE
Volume48
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Cancer screening
  • Endoscopic surveillance
  • Gastroenterology
  • Hepatology
  • Localization
  • Medicine (all)
  • Metaplasia

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