Baclofen in the treatment of persistent hiccup: a case series.

Giovanni Addolorato, Antonio Mirijello, Cristina D'Angelo, Anna Ferrulli, Gabriele Angelo Vassallo, Mariangela Antonelli, Lorenzo Leggio, Raffaele Landolfi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

19 Citazioni (Scopus)

Abstract

Abstract BACKGROUND: Persistent hiccup is a worrying symptom both for patients, because of reduced quality of life, and for physicians, because of frustration for unsuccessful treatments. AIM: To test baclofen administration for the treatment of persistent hiccup. METHOD: We report a series of seven patients affected by persistent hiccup successfully treated with baclofen. RESULTS: Hiccup stopped in all patients after a single administration of the drug. CONCLUSIONS: Baclofen is a GABA(B) receptor agonist. It is conceivable that the reduction of dopamine release by GABA(B) receptor stimulation is able to interrupt hiccup's reflex arc.
Lingua originaleEnglish
pagine (da-a)918-921
Numero di pagine4
Rivistainternal journal of clinical practice
Stato di pubblicazionePubblicato - 2013

Keywords

  • baclofen
  • treatment

Fingerprint Entra nei temi di ricerca di 'Baclofen in the treatment of persistent hiccup: a case series.'. Insieme formano una fingerprint unica.

Cita questo