Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

Francesco Autore; Idanna Innocenti; Marco Luigetti; Nicola Piccirillo; Federica Sora'; Patrizia Chiusolo; Simona Sica; Andrea Bacigalupo; Luca Laurenti

doi:10.1002/hon.2478

Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

Francesco Autore, Idanna Innocenti, Marco Luigetti, Nicola Piccirillo, Federica Sora', Patrizia Chiusolo, Simona Sica, Andrea Bacigalupo, Luca Laurenti

Risultato della ricerca: Contributo in rivista › Articolo in rivista

2 Citazioni (Scopus)

Abstract

POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.

Lingua originale	English
pagine (da-a)	392-398
Numero di pagine	7
Rivista	Hematological Oncology
Volume	36
DOI	https://doi.org/10.1002/hon.2478
Stato di pubblicazione	Pubblicato - 2017

Keywords

ASCT
Cancer Research
Hematology
Lenalidomide
Oncology
Poems

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10.1002/hon.2478

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abstract = "POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.",

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T1 - Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

AU - Autore, Francesco

AU - Innocenti, Idanna

AU - Luigetti, Marco

AU - Piccirillo, Nicola

AU - Sora', Federica

AU - Chiusolo, Patrizia

AU - Sica, Simona

AU - Bacigalupo, Andrea

AU - Laurenti, Luca

PY - 2017

Y1 - 2017

N2 - POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.

AB - POEMS syndrome is a rare paraneoplastic condition, with a poorly understood pathogenesis. High dose chemotherapy followed by autologous stem cell transplantation (ASCT) has been reported to be an effective therapeutic option for patients with good performance status. Here, we review the role of ASCT for POEMS syndrome and discuss indications together with advantages and disadvantages, and related issues such lenalidomide given before or after ASCT, VEGF levels as a marker of disease, and different regimens for stem cell mobilization.

KW - ASCT

KW - Cancer Research

KW - Hematology

KW - Lenalidomide

KW - Oncology

KW - Poems

KW - ASCT

KW - Cancer Research

KW - Hematology

KW - Lenalidomide

KW - Oncology

KW - Poems

UR - http://hdl.handle.net/10807/117522

UR - http://onlinelibrary.wiley.com/journal/10.1002/(issn)1099-1069

U2 - 10.1002/hon.2478

DO - 10.1002/hon.2478

M3 - Article

SN - 0278-0232

VL - 36

SP - 392

EP - 398

JO - Hematological Oncology

JF - Hematological Oncology

ER -

Autologous peripheral blood stem cell transplantation and the role of lenalidomide in patients affected by poems syndrome

Abstract

Keywords

OSS delle Nazioni Unite

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