ATXN2 polyQ intermediate repeats are a modifier of ALS survival

A Chiò; A Calvo; C Moglia; A Canosa; M Brunetti; M Barberis; G Restagno; Amelia Conte; Giulia Bisogni; Giuseppe Marangi; Alice Moncada; Serena Lattante; Marcella Zollino; Mario Sabatelli; A Bagarotti; L Corrado; G Mora; E Bersano; L Mazzini; S. D'Alfonso

doi:10.1212/WNL.0000000000001159

ATXN2 polyQ intermediate repeats are a modifier of ALS survival

A Chiò^*
, A Calvo
, C Moglia
, A Canosa
, M Brunetti
, M Barberis
, G Restagno
, Amelia Conte
, Giulia Bisogni
, Giuseppe Marangi
, Alice Moncada
, Serena Lattante
, Marcella Zollino
, Mario Sabatelli
, A Bagarotti
, L Corrado
, G Mora
, E Bersano
, L Mazzini
, S. D'Alfonso

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

32 Citazioni (Scopus)

Abstract

To analyze the frequency and clinical characteristics of patients with amyotrophic lateral sclerosis (ALS) with intermediate-length (CAG) expansion (encoding 27-33 glutamines, polyQ) in the ATXN2 gene, in a population-based cohort of Italian patients with ALS (discovery cohort), and to replicate the findings in an independent cohort of consecutive patients from an ALS tertiary center (validation cohort).

Lingua originale	Inglese
pagine (da-a)	251-258
Numero di pagine	8
Rivista	Neurology
Volume	84
Numero di pubblicazione	3
DOI	https://doi.org/10.1212/WNL.0000000000001159
Stato di pubblicazione	Pubblicato - 2015

All Science Journal Classification (ASJC) codes

Neurologia (clinica)

Keywords

als

Accesso al documento

10.1212/WNL.0000000000001159

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Chiò, A., Calvo, A., Moglia, C., Canosa, A., Brunetti, M., Barberis, M., Restagno, G., Conte, A., Bisogni, G., Marangi, G., Moncada, A., Lattante, S., Zollino, M., Sabatelli, M., Bagarotti, A., Corrado, L., Mora, G., Bersano, E., Mazzini, L., & D'Alfonso, S. (2015). ATXN2 polyQ intermediate repeats are a modifier of ALS survival. Neurology, 84(3), 251-258. https://doi.org/10.1212/WNL.0000000000001159

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title = "ATXN2 polyQ intermediate repeats are a modifier of ALS survival",

abstract = "To analyze the frequency and clinical characteristics of patients with amyotrophic lateral sclerosis (ALS) with intermediate-length (CAG) expansion (encoding 27-33 glutamines, polyQ) in the ATXN2 gene, in a population-based cohort of Italian patients with ALS (discovery cohort), and to replicate the findings in an independent cohort of consecutive patients from an ALS tertiary center (validation cohort).",

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author = "A Chi{\`o} and A Calvo and C Moglia and A Canosa and M Brunetti and M Barberis and G Restagno and Amelia Conte and Giulia Bisogni and Giuseppe Marangi and Alice Moncada and Serena Lattante and Marcella Zollino and Mario Sabatelli and A Bagarotti and L Corrado and G Mora and E Bersano and L Mazzini and S. D'Alfonso",

year = "2015",

doi = "10.1212/WNL.0000000000001159",

language = "English",

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Chiò, A, Calvo, A, Moglia, C, Canosa, A, Brunetti, M, Barberis, M, Restagno, G, Conte, A, Bisogni, G, Marangi, G, Moncada, A, Lattante, S, Zollino, M , Sabatelli, M, Bagarotti, A, Corrado, L, Mora, G, Bersano, E, Mazzini, L & D'Alfonso, S 2015, 'ATXN2 polyQ intermediate repeats are a modifier of ALS survival', Neurology, vol. 84, n. 3, pagg. 251-258. https://doi.org/10.1212/WNL.0000000000001159

TY - JOUR

T1 - ATXN2 polyQ intermediate repeats are a modifier of ALS survival

AU - Chiò, A

AU - Calvo, A

AU - Moglia, C

AU - Canosa, A

AU - Brunetti, M

AU - Barberis, M

AU - Restagno, G

AU - Conte, Amelia

AU - Bisogni, Giulia

AU - Marangi, Giuseppe

AU - Moncada, Alice

AU - Lattante, Serena

AU - Zollino, Marcella

AU - Sabatelli, Mario

AU - Bagarotti, A

AU - Corrado, L

AU - Mora, G

AU - Bersano, E

AU - Mazzini, L

AU - D'Alfonso, S.

PY - 2015

Y1 - 2015

N2 - To analyze the frequency and clinical characteristics of patients with amyotrophic lateral sclerosis (ALS) with intermediate-length (CAG) expansion (encoding 27-33 glutamines, polyQ) in the ATXN2 gene, in a population-based cohort of Italian patients with ALS (discovery cohort), and to replicate the findings in an independent cohort of consecutive patients from an ALS tertiary center (validation cohort).

AB - To analyze the frequency and clinical characteristics of patients with amyotrophic lateral sclerosis (ALS) with intermediate-length (CAG) expansion (encoding 27-33 glutamines, polyQ) in the ATXN2 gene, in a population-based cohort of Italian patients with ALS (discovery cohort), and to replicate the findings in an independent cohort of consecutive patients from an ALS tertiary center (validation cohort).

KW - als

UR - https://publicatt.unicatt.it/handle/10807/64787

UR - https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=84925953333&origin=inward

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84925953333&origin=inward

U2 - 10.1212/WNL.0000000000001159

DO - 10.1212/WNL.0000000000001159

M3 - Article

SN - 0028-3878

VL - 84

SP - 251

EP - 258

JO - Neurology

JF - Neurology

IS - 3

ER -

ATXN2 polyQ intermediate repeats are a modifier of ALS survival

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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