Attempt to improve transcutateous bilirubinometry: a double blinded study Medick BiliMed versus Respironic BiliCheck

Daniele De Luca, Enrico Zecca, M. Corsello, E. Tiberi, C. Semeraro, Costantino Romagnoli

Risultato della ricerca: Contributo in rivistaArticolo in rivista


OBJECTIVES: To compare the accuracy of a new transcutaneous bilirubinometer, BiliMed (Medick SA, Paris, France) with BiliCheck (Respironics, Marietta, GA, USA), a widely available instrument, and with total serum bilirubin measurement. DESIGN: A prospective double-blind study comparing the two devices was carried out. 686 healthy newborns needing measurement of their bilirubin were enrolled over a 4-month period. Serum and transcutaneous bilirubin measurements were taken with both devices within 15 minutes. The order of use of the instruments was randomised. SETTING: Well-baby nursery ward in a university hospital, tertiary referral centre. RESULTS: The linear regression analysis showed a better correlation between BiliCheck and serum bilirubin (r = 0.75) than between BiliMed and serum bilirubin (r = 0.45). BiliCheck variability (+/-2 SD of the mean bias from serum bilirubin) was within -87.2 to 63.3 micromol/l, while BiliMed variability was within -97.5 to 121.4 micromol/l. The receiver operating characteristic analysis (for serum bilirubin levels >205.2 micromol/l or >239.4 micromol/l) showed significantly higher areas under the curve for BiliCheck than those for BiliMed (p<0.001). CONCLUSIONS: Despite the potential practical advantages of BiliMed, its reduced diagnostic accuracy in comparison with BiliCheck does not justify its use in clinical practice.
Lingua originaleEnglish
pagine (da-a)135-139
Numero di pagine5
Stato di pubblicazionePubblicato - 2007


  • Medick BiliMed
  • Respironics BiliCheck
  • transcutaneous bilirubinometry


Entra nei temi di ricerca di 'Attempt to improve transcutateous bilirubinometry: a double blinded study Medick BiliMed versus Respironic BiliCheck'. Insieme formano una fingerprint unica.

Cita questo