Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

Maurizio Martini; Anna Maria Ferrara; Manuela Giachelia; Emiliano Panieri; Katherine Siminovitch; Tommaso Galeotti; Luigi Maria Larocca; Giovambattista Pani

doi:10.1002/ibd.21814

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

Maurizio Martini, Anna Maria Ferrara, Manuela Giachelia, Emiliano Panieri, Katherine Siminovitch, Tommaso Galeotti, Luigi Maria Larocca, Giovambattista Pani

University of Toronto

Risultato della ricerca: Contributo in rivista › Articolo in rivista

18 Citazioni (Scopus)

Abstract

Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (<55 years). We evaluated whether single nucleotide polymorphisms of the OCTN1 and OCTN2 genes are associated with UC, SCC, and with UC cases with cancer progression (UCCP).

Lingua originale	English
pagine (da-a)	439-448
Numero di pagine	10
Rivista	Inflammatory Bowel Diseases
Volume	18
DOI	https://doi.org/10.1002/ibd.21814
Stato di pubblicazione	Pubblicato - 2012

Keywords

Caco-2 Cells
Colitis, Ulcerative
OCTN1-2

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title = "Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients",

abstract = "Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (<55 years). We evaluated whether single nucleotide polymorphisms of the OCTN1 and OCTN2 genes are associated with UC, SCC, and with UC cases with cancer progression (UCCP).",

keywords = "Caco-2 Cells, Colitis, Ulcerative, OCTN1-2, Caco-2 Cells, Colitis, Ulcerative, OCTN1-2",

author = "Maurizio Martini and Ferrara, {Anna Maria} and Manuela Giachelia and Emiliano Panieri and Katherine Siminovitch and Tommaso Galeotti and Larocca, {Luigi Maria} and Giovambattista Pani",

year = "2012",

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T1 - Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

AU - Martini, Maurizio

AU - Ferrara, Anna Maria

AU - Giachelia, Manuela

AU - Panieri, Emiliano

AU - Siminovitch, Katherine

AU - Galeotti, Tommaso

AU - Larocca, Luigi Maria

AU - Pani, Giovambattista

PY - 2012

Y1 - 2012

N2 - Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (<55 years). We evaluated whether single nucleotide polymorphisms of the OCTN1 and OCTN2 genes are associated with UC, SCC, and with UC cases with cancer progression (UCCP).

AB - Ulcerative colitis (UC) is associated with colorectal cancer. Chronic inflammation may also play a role in the pathogenesis of sporadic colorectal cancer (SCC), particularly in younger patients (<55 years). We evaluated whether single nucleotide polymorphisms of the OCTN1 and OCTN2 genes are associated with UC, SCC, and with UC cases with cancer progression (UCCP).

KW - Caco-2 Cells

KW - Colitis, Ulcerative

KW - OCTN1-2

KW - Caco-2 Cells

KW - Colitis, Ulcerative

KW - OCTN1-2

UR - http://hdl.handle.net/10807/25734

U2 - 10.1002/ibd.21814

DO - 10.1002/ibd.21814

M3 - Article

SN - 1536-4844

VL - 18

SP - 439

EP - 448

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

ER -

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

Abstract

Keywords

OSS delle Nazioni Unite

Accesso al documento

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