Association of high levels of α-defensins and S100A proteins with Candida mannan detection in bronchoalveolar lavage fluid of preterm neonates

Giovanni Vento, Alessandra Lio, Chiara Tirone, Claudia Aurilia, Milena Tana, Andrea Piras, Cinzia Ricci, Sarah Perelli, Costantino Romagnoli, Brunella Posteraro, Federica Iavarone, Tiziana Cabras, Chiara Fanali, Irene Messana, Massimo Castagnola

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

Candida mannan (Mn) detection in bronchoalveolar lavage fluid (BALF) was shown to be useful for earlier identification and preemptive therapy targeting in preterm infants at high risk of invasive Candida infection. We investigated whether early detection of Candida Mn in BALF is associated with the presence of some neutrophilic products, as markers of prenatal infection/inflammation.
Lingua originaleEnglish
pagine (da-a)19-25
Numero di pagine7
RivistaPediatric Research
Volume74
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • Bronchoalveolar Lavage Fluid
  • Candida
  • Chromatography, High Pressure Liquid
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Male
  • S100 Proteins
  • Spectrometry, Mass, Electrospray Ionization
  • alpha-Defensins

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