TY - JOUR
T1 - Association of Body Fat With Health-Related Quality of Life and Depression in Nonagenarians: The Mugello Study.
AU - Giovannini, Silvia
AU - Liperoti, Rosa
AU - Onder, Graziano
AU - Padua, Luca
AU - Coraci, Daniele
AU - Loreti, Claudia
AU - Macchi, Claudio
AU - Laudisio, Alice
AU - Vannetti, Federica
AU - Bonaccorsi, Guglielmo
AU - Boni, Roberta
AU - Castagnoli, Chiara
AU - Cecchi, Francesca
AU - Cesari, Francesca
AU - Epifani, Francesco
AU - Frandi, Roberta
AU - Giusti, Betti
AU - Luisi, Maria Luisa Eliana
AU - Marcucci, Rossella
AU - Molino-Lova, Raffaello
AU - Paperini, Anita
AU - Razzolini, Lorenzo
AU - Sofi, Francesco
AU - Turcan, Nona
AU - Valecchi, Debora
PY - 2019
Y1 - 2019
N2 - OBJECTIVES:
The association of body fat with health status and depression in the oldest old is still debated. The aim of this cross-sectional study is to investigate the association of body fat with health-related quality of life and depression in a sample of nonagenarians.
DESIGN:
Data are from the Mugello study, a community-based project conducted in Italian older adults aged 90 years.
SETTING AND PARTICIPANTS:
Total body fat was assessed by body impedance assessment. Participants were divided into 3 groups according to gender-specific tertiles of body fat percentage (BF%). Self-perceived mental and physical health status were assessed by the Mental Component Summary (MCS) and the Physical Component Summary (PCS) subscales derived from the 12-item Short Form Health Survey. Lower scores of MCS and PCS indicated poorer mental health and physical health status, respectively. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale, and a score ≥5 was used to identify participants with depression.
RESULTS:
The mean age of 251 study participants was 92.5 years, and 173 (68.9%) were women. Participants were included in the low (n = 83), medium (n = 83), and high (n = 85) BF% groups. In the whole sample, mean scores at PCS progressively declined with the increasing BF% group (P = .004). This association was stronger in women, although no significant interaction was observed between the gender and BF% group (P = .63). No significant association between BF% and MCS was documented. Medium and high BF% were associated with a significantly higher probability of depression as compared with low BF% [odds ratio (OR) 2.15, 95% confidence interval (CI) 1.04-4.44, and OR 2.15, 95% CI 1.06-4.34, respectively]. This association was stronger in women, although no significant interaction was observed between gender and BF% group (P = .70).
CONCLUSIONS AND IMPLICATIONS:
High BF% is significantly positively associated with poor health-related quality of life and depression, underpinning the clinical relevance to test BF% in older adults. These associations appear to be stronger in women than in men, highlighting the need to investigate deep inside this gender discrepancy.
AB - OBJECTIVES:
The association of body fat with health status and depression in the oldest old is still debated. The aim of this cross-sectional study is to investigate the association of body fat with health-related quality of life and depression in a sample of nonagenarians.
DESIGN:
Data are from the Mugello study, a community-based project conducted in Italian older adults aged 90 years.
SETTING AND PARTICIPANTS:
Total body fat was assessed by body impedance assessment. Participants were divided into 3 groups according to gender-specific tertiles of body fat percentage (BF%). Self-perceived mental and physical health status were assessed by the Mental Component Summary (MCS) and the Physical Component Summary (PCS) subscales derived from the 12-item Short Form Health Survey. Lower scores of MCS and PCS indicated poorer mental health and physical health status, respectively. Depressive symptoms were assessed using the 15-item Geriatric Depression Scale, and a score ≥5 was used to identify participants with depression.
RESULTS:
The mean age of 251 study participants was 92.5 years, and 173 (68.9%) were women. Participants were included in the low (n = 83), medium (n = 83), and high (n = 85) BF% groups. In the whole sample, mean scores at PCS progressively declined with the increasing BF% group (P = .004). This association was stronger in women, although no significant interaction was observed between the gender and BF% group (P = .63). No significant association between BF% and MCS was documented. Medium and high BF% were associated with a significantly higher probability of depression as compared with low BF% [odds ratio (OR) 2.15, 95% confidence interval (CI) 1.04-4.44, and OR 2.15, 95% CI 1.06-4.34, respectively]. This association was stronger in women, although no significant interaction was observed between gender and BF% group (P = .70).
CONCLUSIONS AND IMPLICATIONS:
High BF% is significantly positively associated with poor health-related quality of life and depression, underpinning the clinical relevance to test BF% in older adults. These associations appear to be stronger in women than in men, highlighting the need to investigate deep inside this gender discrepancy.
KW - Body fat percentage
KW - depression
KW - nonagenarians
KW - physical activity
KW - Body fat percentage
KW - depression
KW - nonagenarians
KW - physical activity
UR - http://hdl.handle.net/10807/132698
U2 - 10.1016/j.jamda.2019.01.128
DO - 10.1016/j.jamda.2019.01.128
M3 - Article
VL - 20
SP - 564
EP - 568
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
SN - 1525-8610
ER -