Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation

A Corsonello; Claudio Pedone; F Lattanzio; Graziano Onder; Raffaele Antonelli Incalzi

doi:10.2165/11588280-000000000-00000

Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation

A Corsonello, Claudio Pedone, F Lattanzio, Graziano Onder, Raffaele Antonelli Incalzi

Universita Campus Bio-Medico di Roma

Risultato della ricerca: Contributo in rivista › Articolo

35 Citazioni (Scopus)

Abstract

Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.

Lingua originale	Inglese
pagine (da-a)	379-390
Numero di pagine	12
Rivista	DRUGS & AGING
Volume	28
Numero di pubblicazione	5
DOI	https://doi.org/10.2165/11588280-000000000-00000
Stato di pubblicazione	Pubblicato - 2011

Keywords

80 and over
Adult
Aged
Biological
Creatine
Drug Toxicity
Female
Glomerular Filtration Rate
Hospitalization
Humans
Hydrophobic and Hydrophilic Interactions
Male
Middle Aged
Models

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10.2165/11588280-000000000-00000

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abstract = "Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.",

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author = "A Corsonello and Claudio Pedone and F Lattanzio and Graziano Onder and {Antonelli Incalzi}, Raffaele",

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AU - Corsonello, A

AU - Pedone, Claudio

AU - Lattanzio, F

AU - Onder, Graziano

AU - Antonelli Incalzi, Raffaele

PY - 2011

Y1 - 2011

N2 - Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.

AB - Reduced renal function increases the risk of adverse drug reactions (ADRs) to hydrosoluble drugs (hADRs). However, the ability of different equations to calculate estimated glomerular filtration rate (eGFR) or estimated creatinine clearance (eCCr) and thereby predict the risk of developing hADRs has not previously been compared.

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KW - Middle Aged

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KW - Aged

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KW - Creatine

KW - Drug Toxicity

KW - Female

KW - Glomerular Filtration Rate

KW - Hospitalization

KW - Humans

KW - Hydrophobic and Hydrophilic Interactions

KW - Male

KW - Middle Aged

KW - Models

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Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation

Abstract

Keywords

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