TY - JOUR
T1 - Assessing the role of minimally invasive radical hysterectomy for early-stage cervical cancer
AU - Bogani, Giorgio
AU - Di Donato, Violante
AU - Muzii, Ludovico
AU - Casarin, Jvan
AU - Ghezzi, Fabio
AU - Malzoni, Mario
AU - Greggi, Stefano
AU - Landoni, Fabio
AU - Bazzurini, Luca
AU - Zanagnolo, Vanna
AU - Multinu, Francesco
AU - Angioli, Roberto
AU - Plotti, Francesco
AU - Caruso, Giuseppe
AU - Fischetti, Margherita
AU - Ferrandina, Maria Gabriella
AU - Palaia, Innocenza
AU - Benedetti Panici, Pierluigi
AU - Scambia, Giovanni
AU - Raspagliesi, Francesco
PY - 2022
Y1 - 2022
N2 - Surgery is the mainstay of treatment in the management of early-stage cervical cancer. Until the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, minimally invasive radical hysterectomy was the recommended approach to treat patients with early-stage disease. The results of the LACC trial questioned the adoption of minimally invasive surgery in cervical cancer. In comparison with the open approach, minimally invasive surgery correlated with worse disease-free and cancer-specific survival. Similarly, other retrospective studies highlighted this correlation, thus corroborating the results of the LACC trials. In the present review, we evaluated current evidence and further prospective of the adoption of minimally invasive radical hysterectomy in cervical cancer. Moreover, we sought to assess some unsolved issues regarding the role of minimally invasive surgery in early-stage cervical cancer patients.
AB - Surgery is the mainstay of treatment in the management of early-stage cervical cancer. Until the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, minimally invasive radical hysterectomy was the recommended approach to treat patients with early-stage disease. The results of the LACC trial questioned the adoption of minimally invasive surgery in cervical cancer. In comparison with the open approach, minimally invasive surgery correlated with worse disease-free and cancer-specific survival. Similarly, other retrospective studies highlighted this correlation, thus corroborating the results of the LACC trials. In the present review, we evaluated current evidence and further prospective of the adoption of minimally invasive radical hysterectomy in cervical cancer. Moreover, we sought to assess some unsolved issues regarding the role of minimally invasive surgery in early-stage cervical cancer patients.
KW - Cervical cancer
KW - Laparoscopy
KW - Radical hysterectomy
KW - Robotic
KW - Cervical cancer
KW - Laparoscopy
KW - Radical hysterectomy
KW - Robotic
UR - http://hdl.handle.net/10807/211402
U2 - 10.1016/j.ejogrb.2022.06.004
DO - 10.1016/j.ejogrb.2022.06.004
M3 - Article
SN - 0301-2115
VL - 275
SP - 64-69-69
JO - EUROPEAN JOURNAL OF OBSTETRICS, GYNECOLOGY, AND REPRODUCTIVE BIOLOGY
JF - EUROPEAN JOURNAL OF OBSTETRICS, GYNECOLOGY, AND REPRODUCTIVE BIOLOGY
ER -
