Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study)

Cesare Colosimo, Kenneth R. Maravilla, M. P. Smith, J. Vymazal, M. Goyal, M. Herman, J. J. Baima, R. Babbel, M. Vaneckova, J. Žižka, M. Urbańczyk-Zawadzka, M. Mechl, A. K. Bag, S. Bastianello, E. Bueltmann, T. Hirai, T. Frattini, M. A. Kirchin, G. Pirovano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

13 Citazioni (Scopus)

Abstract

Gadobutrol (Gadavist) and gadoteridol (ProHance) have similar macrocyclic molecular structures, but gadobutrol is formulated at a 2-fold higher (1 mol/L versus 0.5 mol/L) concentration. We sought to determine whether this difference impacts morphologic contrast-enhanced MR imaging.
Lingua originaleEnglish
pagine (da-a)14-23
Numero di pagine10
RivistaAJNR, AMERICAN JOURNAL OF NEURORADIOLOGY
Volume36
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Agent
  • Brain Tumor
  • Contrast
  • Gadobutrol
  • Gadolinium
  • Gadoteridol
  • Macrocyclic

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