TY - JOUR
T1 - Antimicrobial-resistant Gram-negative bacteria in febrile neutropenic patients with cancer: current epidemiology and clinical impact
AU - Trecarichi, Enrico Maria
AU - Tumbarello, Mario
PY - 2014
Y1 - 2014
N2 - In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.
AB - In the recent years, several studies involving cancer patients have demonstrated a clear trend in the epidemiology of bacterial infections showing a shift in the prevalence from Gram-positive to Gram-negative bacteria and the extensive emergence of antimicrobial-resistant strains among Gram-negatives isolated from the blood. The aim of this systematic review was to examine the recent trends in epidemiology and antimicrobial resistance in Gram-negatives recovered from neutropenic cancer patients, with particular emphasis on the impact of antimicrobial resistance on the clinical outcome of severe infections caused by such microorganisms.
KW - Anti-Bacterial Agents
KW - Drug Resistance, Bacterial
KW - Febrile Neutropenia
KW - Gram-Negative Bacteria
KW - Gram-Negative Bacterial Infections
KW - Humans
KW - Neoplasms
KW - Anti-Bacterial Agents
KW - Drug Resistance, Bacterial
KW - Febrile Neutropenia
KW - Gram-Negative Bacteria
KW - Gram-Negative Bacterial Infections
KW - Humans
KW - Neoplasms
UR - http://hdl.handle.net/10807/65017
U2 - 10.1097/QCO.0000000000000038
DO - 10.1097/QCO.0000000000000038
M3 - Article
SN - 0951-7375
VL - 27
SP - 200
EP - 210
JO - Current Opinion in Infectious Diseases
JF - Current Opinion in Infectious Diseases
ER -