Anti-Rh(c), "Little C," Isoimmunization: The Role of rHuEpo in Preventing Late Anemia

Antonio Alberto Zuppa, Valentina Cardiello, Giovanni Alighieri, Francesco Cota, Annamaria D'Antuono, R Riccardi, P Catenazzi, C. Romagnoli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

The overall prevalence of non-Rh-D isoimmunization seems to lie between 0.15% and 1.1%. Anti-Rh(c) alloimmunization, "little c," occurs in 0.07% of pregnancies and shows a quite broad clinical presentation. Late anemia is a frequent problem occurring in the setting of isoimmunization. It occurs more frequently after intrauterine blood transfusions or exsanguinotransfusion, and it can be thought as a hyporegenerative anemia. The authors describe the use of human recombinant erythropoietin in preventing late anemia in a case of anti-Rh(c) isoimmunization. The use of human recombinant erythropoietin is a valid tool for preventing late-onset anemia due to either anti-Rh-D or non-anti-Rh-D isoimmunization.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaJOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Stato di pubblicazionePubblicato - 2012

Keywords

  • isoimmunization
  • rHuEpo

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