Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Emanuela Bartoccioni; Flavia Scuderi; Giacomo Maria Minicuci; Mariapaola Marino; F. Ciaraffa; Amelia Evoli Stampanoni-B

doi:10.1212/01.wnl.0000228225.23349.5d

Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Emanuela Bartoccioni, Flavia Scuderi, Giacomo Maria Minicuci, Mariapaola Marino, F. Ciaraffa, Amelia Evoli Stampanoni-B^*

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo in rivista

100 Citazioni (Scopus)

Abstract

The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

Lingua originale	English
pagine (da-a)	505-507
Numero di pagine	3
Rivista	Neurology
Volume	67
DOI	https://doi.org/10.1212/01.wnl.0000228225.23349.5d
Stato di pubblicazione	Pubblicato - 2006

Keywords

Adolescent
Adult
Aged
Antibodies
Child
Female
Humans
Male
Middle Aged
Myasthenia Gravis
Receptor Protein-Tyrosine Kinases
Receptors, Cholinergic
Severity of Illness Index
Statistics as Topic

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10.1212/01.wnl.0000228225.23349.5d

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abstract = "The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.",

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doi = "10.1212/01.wnl.0000228225.23349.5d",

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volume = "67",

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AU - Bartoccioni, Emanuela

AU - Scuderi, Flavia

AU - Minicuci, Giacomo Maria

AU - Marino, Mariapaola

AU - Ciaraffa, F.

AU - Evoli Stampanoni-B, Amelia

PY - 2006

Y1 - 2006

N2 - The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

AB - The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

KW - Adolescent

KW - Adult

KW - Aged

KW - Antibodies

KW - Child

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myasthenia Gravis

KW - Receptor Protein-Tyrosine Kinases

KW - Receptors, Cholinergic

KW - Severity of Illness Index

KW - Statistics as Topic

KW - Adolescent

KW - Adult

KW - Aged

KW - Antibodies

KW - Child

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myasthenia Gravis

KW - Receptor Protein-Tyrosine Kinases

KW - Receptors, Cholinergic

KW - Severity of Illness Index

KW - Statistics as Topic

UR - http://hdl.handle.net/10807/163601

U2 - 10.1212/01.wnl.0000228225.23349.5d

DO - 10.1212/01.wnl.0000228225.23349.5d

M3 - Article

SN - 0028-3878

VL - 67

SP - 505

EP - 507

JO - Neurology

JF - Neurology

ER -

Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Abstract

Keywords

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