Anti-HLA donor-specific antibodies in allogeneic stem cell transplantation: management and desensitization protocol

Luca Laurenti, Robin Foa, Ursula La Rocca, Maria Paola Perrone, Alfonso Piciocchi, Paola Cinti, Walter Barberi, Maria Gozzer, Mahnaz Shafii Baftii, Giovanni Fernando Torelli, Luisa Quattrocchi, Paola Gesuiti, Roberto Lattanzi, Claudio Cavallari, Roberto Ricci, Gabriella Girelli, Anna Paola Iori

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

The role of antibodies directed against the human leukocyte antigen (HLA) system has been well analyzed in rejection of solid organ transplantations [1, 2] and in transfusion medicine [3]. In the setting of allogeneic hematopoietic stem cells transplantation (HSCT), only in the recent years their importance has been better defined, even though anti-HLA antibodies are frequently detectable in hematologic patients, due to sensitization from multiple transfusions, usually before the introduction of online universal leukoreduction, previous transplantations, and pregnancies in female patients.
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaBone Marrow Transplantation
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • CLL

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