TY - JOUR
T1 - Anti-AChR-negative myasthenia gravis: clinical and immunological features
AU - Evoli Stampanoni-B, Amelia
AU - Bartoccioni, Emanuela
AU - Batocchi, Anna Paola
AU - Scuderi, Flavia
AU - Tonali, Pietro Attilio
PY - 1989
Y1 - 1989
N2 - The clinical and immunological characteristics of myasthenia gravis (MG) patients without detectable anti-Acetylcholine Receptor (anti-AChR) antibody were studied. Sixty anti-AChR negative MG patients were compared with 287 anti-AChR positive cases. Significant differences were found with respect to the sex incidence, the disease severity and the thymic pathology, while the age at the onset of the disease, the presence of other auto-antibodies and the efficacy of medical treatments were similar in the two groups of patients. Anti-AChR-negative MG could have pathogenetic mechanisms different from the antibody-positive disease.
AB - The clinical and immunological characteristics of myasthenia gravis (MG) patients without detectable anti-Acetylcholine Receptor (anti-AChR) antibody were studied. Sixty anti-AChR negative MG patients were compared with 287 anti-AChR positive cases. Significant differences were found with respect to the sex incidence, the disease severity and the thymic pathology, while the age at the onset of the disease, the presence of other auto-antibodies and the efficacy of medical treatments were similar in the two groups of patients. Anti-AChR-negative MG could have pathogenetic mechanisms different from the antibody-positive disease.
KW - Anti-AChR-negative
KW - Myasthenia Gravis
KW - Anti-AChR-negative
KW - Myasthenia Gravis
UR - http://hdl.handle.net/10807/18626
M3 - Article
SN - 0147-958X
VL - 12
SP - 104
EP - 109
JO - CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE
JF - CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE
ER -