Angina after percutaneous coronary intervention: The need for precision medicine

Giampaolo Niccoli, Rocco Antonio Montone, Gaetano Antonio Lanza, Filippo Crea

Risultato della ricerca: Contributo in rivistaArticolo in rivista

23 Citazioni (Scopus)


Persistence or recurrence of angina after successful percutaneous coronary intervention (PCI) represent an important clinical issue involving from one fifth to one third of patients undergoing myocardial revascularization at one-year follow-up. A systematic approach to this syndrome is strongly needed. Precision medicine is particularly important in addressing angina after successful PCI because of the multiple underlying causes. Restenosis or coronary atherosclerosis progression explain symptom recurrence after successful PCI in some patients, while functional causes, including vasomotor abnormalities of epicardial coronary arteries and/or coronary microvascular dysfunction, explain symptoms in the remaining patients. In this review, we summarize the mechanisms of persistent or recurrent angina after PCI, proposing a diagnostic algorithm and a systematic therapeutic approach.
Lingua originaleEnglish
pagine (da-a)14-19
Numero di pagine6
RivistaInternational Journal of Cardiology
Stato di pubblicazionePubblicato - 2017


  • Angina
  • Cardiology and Cardiovascular Medicine
  • Microvascular dysfunction
  • Percutaneous coronary intervention


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