Gelatin, a collagen protein obtained from cow and pig bones and fish skin is widely used, by the hydrolysis of collagen, in food preparations (sweets, yoghurt, etc.) and as a stabilizer in the pharmaceutical industry. In particular it could be found as an ingredient of drug capsules, plasma expanders, vaccines and plasma substitutes. Systemic allergic reactions to gelatin-containing vaccines and drugs have been proven by anti-gelatin IgE assay [1–3] and by the Basophil Activation Test (BAT) . Bovine gelatin sensitization is commonly associated with cow milk allergy and beef allergy . We report the case of a 14-year-old patient affected by cow’s milk allergy, who experienced lip paraesthesia, generalized itching and dyspnoea with bronchospasm after the ingestion of lyophilised ebastine; the reaction was handled in the emergency room with intramuscular and aerosolized epinephrine, systemic corticosteroids and antihistamines.
|Numero di pagine||2|
|Rivista||Postepy Dermatologii I Alergologii|
|Stato di pubblicazione||Pubblicato - 2017|
- bovine gelatin basophil activation test