Analysis of the arrhythmogenic substrate in human heart failure

Sara Partemi; Montserrat Batlle; Paola Berne; Antonio Berruezo; Begoña Campos; Luis Mont; Helena Riuró; Eulalia Roig; Felix Pérez-Villa; Jose Ortiz; Vincenzo Lorenzo Pascali; Antonio Oliva; Ramon Brugada; Josep Brugada

doi:10.1016/j.carpath.2012.07.003

Analysis of the arrhythmogenic substrate in human heart failure

Sara Partemi
, Montserrat Batlle
, Paola Berne
, Antonio Berruezo
, Begoña Campos
, Luis Mont
, Helena Riuró
, Eulalia Roig
, Felix Pérez-Villa
, Jose Ortiz
, Vincenzo Lorenzo Pascali
, Antonio Oliva
, Ramon Brugada
, Josep Brugada

University of Barcelona
University of Girona
Autonomous University of Barcelona

Risultato della ricerca: Contributo in rivista › Articolo › peer review

9 Citazioni (Scopus)

Abstract

The mechanism of sudden cardiac death in patients with heart failure (HF) is uncertain. Both electrical instability and structural remodelling could be factors that lead to fatal arrhythmias. We sought to analyse the expression of the sodium (SCN5A) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of human HF and of non-diseased hearts under different post-mortem intervals.

Lingua originale	Inglese
pagine (da-a)	133-140
Numero di pagine	8
Rivista	Cardiovascular Pathology
Volume	22
DOI	https://doi.org/10.1016/j.carpath.2012.07.003
Stato di pubblicazione	Pubblicato - 2013

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Keywords

arrhythmogenic substrate in human heart failure
sudden cardiac death

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10.1016/j.carpath.2012.07.003

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title = "Analysis of the arrhythmogenic substrate in human heart failure",

abstract = "The mechanism of sudden cardiac death in patients with heart failure (HF) is uncertain. Both electrical instability and structural remodelling could be factors that lead to fatal arrhythmias. We sought to analyse the expression of the sodium (SCN5A) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of human HF and of non-diseased hearts under different post-mortem intervals.",

keywords = "arrhythmogenic substrate in human heart failure, sudden cardiac death, arrhythmogenic substrate in human heart failure, sudden cardiac death",

author = "Sara Partemi and Montserrat Batlle and Paola Berne and Antonio Berruezo and Bego{\~n}a Campos and Luis Mont and Helena Riur{\'o} and Eulalia Roig and Felix P{\'e}rez-Villa and Jose Ortiz and Pascali, \{Vincenzo Lorenzo\} and Antonio Oliva and Ramon Brugada and Josep Brugada",

year = "2013",

doi = "10.1016/j.carpath.2012.07.003",

language = "English",

volume = "22",

pages = "133--140",

journal = "Cardiovascular Pathology",

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TY - JOUR

T1 - Analysis of the arrhythmogenic substrate in human heart failure

AU - Partemi, Sara

AU - Batlle, Montserrat

AU - Berne, Paola

AU - Berruezo, Antonio

AU - Campos, Begoña

AU - Mont, Luis

AU - Riuró, Helena

AU - Roig, Eulalia

AU - Pérez-Villa, Felix

AU - Ortiz, Jose

AU - Pascali, Vincenzo Lorenzo

AU - Oliva, Antonio

AU - Brugada, Ramon

AU - Brugada, Josep

PY - 2013

Y1 - 2013

N2 - The mechanism of sudden cardiac death in patients with heart failure (HF) is uncertain. Both electrical instability and structural remodelling could be factors that lead to fatal arrhythmias. We sought to analyse the expression of the sodium (SCN5A) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of human HF and of non-diseased hearts under different post-mortem intervals.

AB - The mechanism of sudden cardiac death in patients with heart failure (HF) is uncertain. Both electrical instability and structural remodelling could be factors that lead to fatal arrhythmias. We sought to analyse the expression of the sodium (SCN5A) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of human HF and of non-diseased hearts under different post-mortem intervals.

KW - arrhythmogenic substrate in human heart failure

KW - sudden cardiac death

KW - arrhythmogenic substrate in human heart failure

KW - sudden cardiac death

UR - http://hdl.handle.net/10807/41474

U2 - 10.1016/j.carpath.2012.07.003

DO - 10.1016/j.carpath.2012.07.003

M3 - Article

SN - 1054-8807

VL - 22

SP - 133

EP - 140

JO - Cardiovascular Pathology

JF - Cardiovascular Pathology

ER -

Analysis of the arrhythmogenic substrate in human heart failure

Abstract

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Keywords

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