Analysis of the arrhythmogenic substrate in human heart failure

Vincenzo Lorenzo Pascali, Antonio Oliva, Sara Partemi, Montserrat Batlle, Paola Berne, Antonio Berruezo, Begoña Campos, Luis Mont, Helena Riuró, Eulalia Roig, Felix Pérez-Villa, Jose Ortiz, Ramon Brugada, Josep Brugada

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

9 Citazioni (Scopus)

Abstract

The mechanism of sudden cardiac death in patients with heart failure (HF) is uncertain. Both electrical instability and structural remodelling could be factors that lead to fatal arrhythmias. We sought to analyse the expression of the sodium (SCN5A) and potassium (KCND3) channels as well as the fibrosis content in the ventricles of human HF and of non-diseased hearts under different post-mortem intervals.
Lingua originaleEnglish
pagine (da-a)133-140
Numero di pagine8
RivistaCardiovascular Pathology
Volume22
DOI
Stato di pubblicazionePubblicato - 2013

Keywords

  • arrhythmogenic substrate in human heart failure
  • sudden cardiac death

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