Analysis of conjugated bile acids by high performance liquid chromatography and mass spectrometry

Risultato della ricerca: Contributo in rivistaArticolo

Abstract

Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy subjects were examined. The amounts of each tauro- and glycoconjugated bile acid as trifluoracetate were determined by mass fragmentography. Quantitation of at least 1 ng of each bile acid was possible.
Lingua originaleInglese
pagine (da-a)90-95
Numero di pagine6
RivistaLipids
Volume18
Stato di pubblicazionePubblicato - 1983

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

  1. SDG 3 - Salute e benessere
    SDG 3 Salute e benessere

Keywords

  • Animals
  • Bile Acids and Salts
  • Chromatography, High Pressure Liquid
  • Gas Chromatography-Mass Spectrometry
  • Structure-Activity Relationship

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