Abstract
Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy subjects were examined. The amounts of each tauro- and glycoconjugated bile acid as trifluoracetate were determined by mass fragmentography. Quantitation of at least 1 ng of each bile acid was possible.
| Lingua originale | Inglese |
|---|---|
| pagine (da-a) | 90-95 |
| Numero di pagine | 6 |
| Rivista | Lipids |
| Volume | 18 |
| Stato di pubblicazione | Pubblicato - 1983 |
Keywords
- Animals
- Bile Acids and Salts
- Chromatography, High Pressure Liquid
- Gas Chromatography-Mass Spectrometry
- Structure-Activity Relationship
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