Amniotic membrane and amniotic fluid-derived cells: potential tools for regenerative medicine?

Ornella Parolini, Maddalena Soncini, Marco Evangelista, Dörthe Schmidt

Risultato della ricerca: Contributo in rivistaArticolo in rivista

122 Citazioni (Scopus)

Abstract

Human amniotic membranes and amniotic fluid have attracted increasing attention in recent years as a possible reserve of stem cells that may be useful for clinical application in regenerative medicine. Many studies have been conducted to date in terms of the differentiation potential of these cells, with several reports demonstrating that cells from both the amniotic fluid and membrane display high plasticity. In addition, cells from the amniotic membrane have also been shown to display immunomodulatory characteristics both in vivo and in vitro, which could make them useful in an allotransplantation setting. Here, we provide an overview comparing the latest findings regarding the stem characteristics of cells from both the amniotic membrane and amniotic fluid, as well as on the potential utility of these cells for future clinical application in regenerative medicine.
Lingua originaleEnglish
pagine (da-a)275-291
Numero di pagine17
RivistaRegenerative Medicine
Volume4
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Amnion
  • Amniotic Fluid
  • Animals
  • Humans
  • Regenerative Medicine
  • Stem Cell Transplantation
  • Stem Cells

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