Alpha-1-antitrypsin protease inhibitor SZ phenotype and liver cirrhosis

Antonella Coli, Giulio Bigotti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

In the light of recent findings concerning the importance of intermediate alpha 1-antitrypsin deficiency in the development of chronic liver disease and of hepatocellular carcinoma, we report the case of a 56-year-old woman affected by cirrhosis with significant features of liver cell dysplasia associated with intermediate alpha 1-antitrypsin deficiency (protease inhibitor SZ phenotype). In our paper we emphasize the importance of a precocious diagnosis and identification of individuals carrying the Z allele, also heterozygous.
Lingua originaleEnglish
pagine (da-a)54-60
Numero di pagine7
RivistaAPPLIED PATHOLOGY
Volume7
Stato di pubblicazionePubblicato - 1989

Keywords

  • Female
  • Humans
  • Liver Cirrhosis
  • Middle Aged
  • Phenotype
  • alpha 1-Antitrypsin
  • alpha 1-Antitrypsin Deficiency

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