Abstract
A recent meta-analysis has indicated that, in patients with dementia, the use of atypical antipsychotics is associated with an excess mortality. Later observational studies have suggested that conventional antipsychotics may pose an even greater risk of death. None of these studies could evaluate the risk associated with single antipsychotics nor could they provide any conclusive evidence concerning the risk among nursing home residents. We conducted a retrospective cohort study to compare the risk of death associated with atypical and conventional antipsychotics in a large population of nursing home residents with dementia.
| Lingua originale | Inglese |
|---|---|
| pagine (da-a) | 1340-1347 |
| Numero di pagine | 8 |
| Rivista | Journal of Clinical Psychiatry |
| Volume | 70 |
| Numero di pubblicazione | 10 |
| DOI | |
| Stato di pubblicazione | Pubblicato - 2009 |
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Keywords
- 80 and over
- Aged
- Alzheimer Disease
- Antipsychotic Agents
- Cardiovascular Diseases
- Cause of Death
- Cerebrovascular Disorders
- Cohort Studies
- Comorbidity
- Dementia
- Female
- Follow-Up Studies
- Humans
- Male
- Nursing Homes
- Retrospective Studies
- Risk Factors
- Survival Analysis
- Time Factors
- United States
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