Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test

Simona Panunzi; Andrea De Gaetano; Geltrude Mingrone

doi:10.1186/1742-4682-7-9

Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test

Simona Panunzi, Andrea De Gaetano, Geltrude Mingrone

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28 Citazioni (Scopus)

Abstract

The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.

Lingua originale	English
pagine (da-a)	9-9
Numero di pagine	1
Rivista	Theoretical Biology and Medical Modelling
Volume	7
DOI	https://doi.org/10.1186/1742-4682-7-9
Stato di pubblicazione	Pubblicato - 2010

Keywords

Glucose Tolerance Test
Humans
Insulin Resistance
Models, Biological

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10.1186/1742-4682-7-9

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abstract = "The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.",

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AU - De Gaetano, Andrea

AU - Mingrone, Geltrude

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N2 - The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.

AB - The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of Variation (CV) less than 52%). The recently proposed Single Delay Model (SDM) is evaluated as a practical alternative.

KW - Glucose Tolerance Test

KW - Humans

KW - Insulin Resistance

KW - Models, Biological

KW - Glucose Tolerance Test

KW - Humans

KW - Insulin Resistance

KW - Models, Biological

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ER -

Advantages of the single delay model for the assessment of insulin sensitivity from the intravenous glucose tolerance test

Abstract

Keywords

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