Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials

Antonino Buffon; Felicita Andreotti; Ep Navarese; Pa Gurbel; M Kozinski; A Kubica; G Musumeci; A Cremonesi; L Tavazzi; J Kubica; F. Castriota

doi:10.1016/j.atherosclerosis.2011.11.001

Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials

Antonino Buffon, Felicita Andreotti, Ep Navarese, Pa Gurbel, M Kozinski, A Kubica, G Musumeci, A Cremonesi, L Tavazzi, J Kubica, F. Castriota

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

29 Citazioni (Scopus)

Abstract

Adjunctive therapy with adenosine has been shown to improve coronary flow in patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine can effectively reduce adverse clinical events. The aim of our study was to perform a meta-analysis of all randomized controlled trials (RCTs) investigating angiographic and clinical outcomes in ACS patients undergoing PCI or thrombolysis and receiving adjunctive adenosine therapy vs. placebo.

Lingua originale	English
pagine (da-a)	1-7
Numero di pagine	7
Rivista	ATHEROSCLEROSIS
Volume	222
DOI	https://doi.org/10.1016/j.atherosclerosis.2011.11.001
Stato di pubblicazione	Pubblicato - 2012

Keywords

acute coronary syndrome
adenosine

Accesso al documento

10.1016/j.atherosclerosis.2011.11.001

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Buffon, A., Andreotti, F., Navarese, E., Gurbel, P., Kozinski, M., Kubica, A., Musumeci, G., Cremonesi, A., Tavazzi, L., Kubica, J., & Castriota, F. (2012). Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials. ATHEROSCLEROSIS, 222, 1-7. https://doi.org/10.1016/j.atherosclerosis.2011.11.001

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title = "Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials",

abstract = "Adjunctive therapy with adenosine has been shown to improve coronary flow in patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine can effectively reduce adverse clinical events. The aim of our study was to perform a meta-analysis of all randomized controlled trials (RCTs) investigating angiographic and clinical outcomes in ACS patients undergoing PCI or thrombolysis and receiving adjunctive adenosine therapy vs. placebo.",

keywords = "acute coronary syndrome, adenosine, acute coronary syndrome, adenosine",

author = "Antonino Buffon and Felicita Andreotti and Ep Navarese and Pa Gurbel and M Kozinski and A Kubica and G Musumeci and A Cremonesi and L Tavazzi and J Kubica and F. Castriota",

year = "2012",

doi = "10.1016/j.atherosclerosis.2011.11.001",

language = "English",

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Buffon, A , Andreotti, F, Navarese, E, Gurbel, P, Kozinski, M, Kubica, A, Musumeci, G, Cremonesi, A, Tavazzi, L, Kubica, J & Castriota, F 2012, 'Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials', ATHEROSCLEROSIS, vol. 222, pagg. 1-7. https://doi.org/10.1016/j.atherosclerosis.2011.11.001

Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials. / Buffon, Antonino ; Andreotti, Felicita; Navarese, Ep; Gurbel, Pa; Kozinski, M; Kubica, A; Musumeci, G; Cremonesi, A; Tavazzi, L; Kubica, J; Castriota, F.

In: ATHEROSCLEROSIS, Vol. 222, 2012, pag. 1-7.

Risultato della ricerca: Contributo in rivista › Articolo in rivista › peer review

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T1 - Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials

AU - Buffon, Antonino

AU - Andreotti, Felicita

AU - Navarese, Ep

AU - Gurbel, Pa

AU - Kozinski, M

AU - Kubica, A

AU - Musumeci, G

AU - Cremonesi, A

AU - Tavazzi, L

AU - Kubica, J

AU - Castriota, F.

PY - 2012

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N2 - Adjunctive therapy with adenosine has been shown to improve coronary flow in patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine can effectively reduce adverse clinical events. The aim of our study was to perform a meta-analysis of all randomized controlled trials (RCTs) investigating angiographic and clinical outcomes in ACS patients undergoing PCI or thrombolysis and receiving adjunctive adenosine therapy vs. placebo.

AB - Adjunctive therapy with adenosine has been shown to improve coronary flow in patients with acute coronary syndromes (ACS); it is unclear, however, whether adenosine can effectively reduce adverse clinical events. The aim of our study was to perform a meta-analysis of all randomized controlled trials (RCTs) investigating angiographic and clinical outcomes in ACS patients undergoing PCI or thrombolysis and receiving adjunctive adenosine therapy vs. placebo.

KW - acute coronary syndrome

KW - adenosine

KW - acute coronary syndrome

KW - adenosine

UR - http://hdl.handle.net/10807/11615

U2 - 10.1016/j.atherosclerosis.2011.11.001

DO - 10.1016/j.atherosclerosis.2011.11.001

M3 - Article

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JO - ATHEROSCLEROSIS

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SN - 1879-1484

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