Adaptive Immunity Dysregulation in Acute Coronary Syndromes: From Cellular and Molecular Basis to Clinical Implications

Giovanna Liuzzo, Filippo Crea, Davide Flego, Cornelia M. Weyand

Risultato della ricerca: Contributo in rivistaArticolo in rivista

28 Citazioni (Scopus)

Abstract

[Ita:]Although the early outcome of acute coronary syndrome (ACS) has considerably improved in the last decade, cardiovascular diseases still represent the main cause of morbidity and mortality worldwide. This is mainly because recurrence of ACS eventually leads to the pandemics of heart failure and sudden cardiac death, thus calling for a reappraisal of the mechanisms responsible for coronary instability. This review discusses recent advances in our understanding of how adaptive immunity contributes to the pathogenesis of ACS and the clinical implications that arise from these new pathogenic concepts.
Lingua originaleEnglish
pagine (da-a)2107-2117
Numero di pagine11
RivistaJOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume68
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • outcome
  • pathogenesis
  • signaling
  • treatment

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