Acute pancreatitis associated with primary hyperparathyroidism

Alberto Biondi, Roberto Persiani, Domenico D'Ugo, Manuela Marchese, Ferdinando Carlo Maria Cananzi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

7 Citazioni (Scopus)

Abstract

Coexistence of primary hyperparathyroidism and acute pancreatitis has widely been reported in literature, but a causal relationship remains controversial. A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported. In this patient a reduction of serum calcium level was obtained with medical therapy and resulted in the resolution of acute pancreatitis symptoms within 10 days. At the same time a parathyroid adenoma was clinically identified and elective parathyroidectomy was performed with complete normalization of intact parathyroid hormone and serum calcium level. At three-year follow-up, no recurrence or complications of pancreatitis were documented. The presented case suggests a cause and effect relationship between acute pancreatitis and severe hypercalcemia which should be kept in mind in the differential diagnosis of non-biliary, non-alcoholic acute pancreatitis. Reduction of hypercalcemia with medical treatment can represent a good chance for elective surgical neck exploration.
Lingua originaleEnglish
pagine (da-a)135-138
Numero di pagine4
RivistaUpdates in Surgery
Volume63
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Acute Disease
  • Adenoma
  • Combined Modality Therapy
  • Female
  • Humans
  • Hypercalcemia
  • Hyperparathyroidism, Primary
  • Middle Aged
  • Pancreatitis
  • Parathyroid Neoplasms
  • Parathyroidectomy
  • Tomography, X-Ray Computed

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