TY - JOUR
T1 - Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management
AU - Niccoli, Giampaolo
AU - Scalone, Giancarla
AU - Crea, Filippo
PY - 2015
Y1 - 2015
N2 - Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.
AB - Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.
KW - Acute myocardial infarction
KW - No obstructive coronary atherosclerosis
KW - Acute myocardial infarction
KW - No obstructive coronary atherosclerosis
UR - http://hdl.handle.net/10807/66151
U2 - 10.1093/eurheartj/ehu469
DO - 10.1093/eurheartj/ehu469
M3 - Article
SN - 0195-668X
VL - 36
SP - 475
EP - 481
JO - European Heart Journal
JF - European Heart Journal
ER -