Acute liver failure in Still’s disease relapse during pregnancy: case report and discussion of a possible trigger role of DILI

Sara De Carolis, Marco Biolato, Cristopher Oddy

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Background: Still's disease is a rare systemic inflammatory disease with frequent but generally mild liver involvement. The most common cause of acute liver failure in western countries is drug-induced liver injury, while it has rarely been reported in subjects suffering from Still’s disease. Case presentation: We report a case of a young woman presenting with SD reactivation in pregnancy and acute liver failure after delivery with a possible triggering role of drug induced liver injury. Conclusions: The prompt recognition of Still's disease reactivation allowed early introduction of steroid therapy and resolution of the clinical picture. We discuss potential factors precipitating ALF in this case, and implications for the diagnosis and management of such patients.
Lingua originaleEnglish
pagine (da-a)1-6
Numero di pagine6
RivistaBMC Gastroenterology
Volume21
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • Acute liver failure
  • Acute onset Still’s disease
  • ALF case report
  • Drug induced liver failure
  • Chronic Disease
  • Still's Disease, Adult-Onset
  • Humans
  • Pregnancy
  • Recurrence
  • Liver Failure, Acute
  • Female

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