TY - JOUR
T1 - ACUTE CHOLESTASIS: ATYPICAL ONSET OF KAWASAKI DISEASE
AU - Valentini, Piero
AU - Ausili, Emanuele
AU - Schiavino, Alessandra
AU - Angelone, Donatella Francesca
AU - Focarelli, Benedetta
AU - De Rosa, Gabriella
AU - Ranno, Orazio Gaetano
PY - 2008
Y1 - 2008
N2 - Atypical onset of Kawasaki disease (KD) is a frequent problem leading to diagnostic mistake. Acute cholestasis and liver involvement occur occasionally as minor manifestation of KD. We report the case of a 6-year-old boy presenting fever, jaundice, abdominal pain, and ascites who subsequently developed typical KD clinical pattern just at the same time of echocardiographic coronary arteries anomalies. Abdominal radiological evaluation was normal and seroimmunologic markers resulted negative. Shortly after intravenous immunoglobulin and acetylsalicylic acid administration the clinical features disappeared. KD should be considered in differential diagnosis in children with cholestasis, abdominal pain and fever of unknown etiology.
AB - Atypical onset of Kawasaki disease (KD) is a frequent problem leading to diagnostic mistake. Acute cholestasis and liver involvement occur occasionally as minor manifestation of KD. We report the case of a 6-year-old boy presenting fever, jaundice, abdominal pain, and ascites who subsequently developed typical KD clinical pattern just at the same time of echocardiographic coronary arteries anomalies. Abdominal radiological evaluation was normal and seroimmunologic markers resulted negative. Shortly after intravenous immunoglobulin and acetylsalicylic acid administration the clinical features disappeared. KD should be considered in differential diagnosis in children with cholestasis, abdominal pain and fever of unknown etiology.
KW - ACUTE CHOLESTASIS
KW - ACUTE CHOLESTASIS
UR - http://hdl.handle.net/10807/32999
U2 - 10.1016/j.dld.2007.10.010
DO - 10.1016/j.dld.2007.10.010
M3 - Article
SN - 1590-8658
VL - 40
SP - 582
EP - 584
JO - Digestive and Liver Disease
JF - Digestive and Liver Disease
ER -