Actual concept of "probiotics": is it more functional to science or business?

Michele Caselli, Francesca Cassol, Girolamo Calò, John Holton, Giovanni Zuliani, Antonio Gasbarrini

Risultato della ricerca: Contributo in rivistaArticolo in rivista

25 Citazioni (Scopus)


It is our contention that the concept of a probiotic as a living bacterium providing unspecified health benefits is inhibiting the development and establishment of an evidence base for the growing field of pharmacobiotics. We believe this is due in part to the current regulatory framework, lack of a clear definition of a probiotic, the ease with which currently defined probiotics can be positioned in the market place, and the enormous profits earned for minimum investment in research. To avoid this, we believe the following two actions are mandatory: international guidelines by a forum of stakeholders made available to scientists and clinicians, patient organizations, and governments; public research funds made available to the scientific community for performing independent rigorous studies both at the preclinical and clinical levels.
Lingua originaleEnglish
pagine (da-a)1527-1540
Numero di pagine14
RivistaWorld Journal of Gastroenterology
Stato di pubblicazionePubblicato - 2013


  • Animals
  • Bacteria
  • Biomedical Research
  • Evidence-Based Medicine
  • Government Regulation
  • Guidelines
  • Health Care Costs
  • Health Care Sector
  • Health Policy
  • Humans
  • Market
  • Metanalysis
  • Practice Guidelines as Topic
  • Probiotics
  • Regulations
  • Terminology as Topic
  • Treatment Outcome


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