Abstract
We describe the case of a 20-year-old man who developed an obstructive bronchial reaction accompanied by a maculopapular facial rash 8 h after an aerosol treatment with the mucolytic drug stepronin. The results of intradermal and patch testing with stepronin, together with those of bronchial challenge and histologic findings in patch-tested skin, indicate that the patient's reaction involved an accelerated cell-mediated mechanism of hypersensitivity. Bronchial challenges with methacholine demonstrated a transient increase in nonspecific bronchial hyperreactivity.
Lingua originale | English |
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pagine (da-a) | 269-271 |
Numero di pagine | 3 |
Rivista | ALLERGY |
Volume | 51 |
DOI | |
Stato di pubblicazione | Pubblicato - 1996 |
Keywords
- broncho-obstructive reaction
- delayed hypersensitivity
- stepronin