Accelerated cell-mediated broncho-obstructive reaction to inhaled stepronin: A case report

Flaminio Mormile, Antonino Romano

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

We describe the case of a 20-year-old man who developed an obstructive bronchial reaction accompanied by a maculopapular facial rash 8 h after an aerosol treatment with the mucolytic drug stepronin. The results of intradermal and patch testing with stepronin, together with those of bronchial challenge and histologic findings in patch-tested skin, indicate that the patient's reaction involved an accelerated cell-mediated mechanism of hypersensitivity. Bronchial challenges with methacholine demonstrated a transient increase in nonspecific bronchial hyperreactivity.
Lingua originaleEnglish
pagine (da-a)269-271
Numero di pagine3
RivistaALLERGY
Volume51
DOI
Stato di pubblicazionePubblicato - 1996

Keywords

  • broncho-obstructive reaction
  • delayed hypersensitivity
  • stepronin

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