TY - JOUR
T1 - A Rare Case of Ectopic Adrenocorticotropic Hormone Syndrome Caused by a Metastatic Neuroendocrine Tumor of the Pancreas Detected by 68Ga-DOTANOC and 18F-FDG PET/CT
AU - Treglia, Giorgio
AU - Salomone, Enrica
AU - Petrone, Gianluigi
AU - Giaccari, Andrea
AU - Rindi, Guido
AU - Rufini, Vittoria
PY - 2013
Y1 - 2013
N2 - We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a Ga-DOTANOC and a F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.
AB - We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a Ga-DOTANOC and a F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.
KW - CUSHING ECTOPICO
KW - ECTOPIC ACTH SYNDROME
KW - F-FDG
KW - Ga-DOTANOC
KW - NEUROENDOCRINE TUMORS
KW - TUMORI ENUROENDOCRINI
KW - CUSHING ECTOPICO
KW - ECTOPIC ACTH SYNDROME
KW - F-FDG
KW - Ga-DOTANOC
KW - NEUROENDOCRINE TUMORS
KW - TUMORI ENUROENDOCRINI
UR - http://hdl.handle.net/10807/42573
UR - http://journals.lww.com/nuclearmed/pages/results.aspx?k=giaccari%20contenttype%3a%22ejournals+content+article+page%22%20contenttype%3a%22blogposts%22%20contenttype%3a%22blogcomments%22%20contenttype%3a%22ejournals+content+image%22%20contenttype%3a%22podcasts%22%20contenttype%3a%22videos%22&searchauthors=giaccari&scope=allissues&txtkeywords=giaccari
U2 - 10.1097/RLU.0b013e318279ec68
DO - 10.1097/RLU.0b013e318279ec68
M3 - Article
SN - 0363-9762
VL - 2013
SP - N/A-N/A
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
ER -