A Randomized Blinded Retrospective Study: the combined use of Micro-needling Technique, Low-Level Laser Therapy and Autologous Non-Activated Platelet-Rich Plasma improves Hair Re-Growth in patients with Androgenic Alopecia

Simone Garcovich, Pietro Gentile, Laura Dionisi, Jacopo Pizzicannella, Barbara De Angelis, Domenico De Fazio

Risultato della ricerca: Contributo in rivistaArticolo in rivista

6 Citazioni (Scopus)

Abstract

Introduction: Mini-invasive therapies based on autologous non-activated Platelet-Rich Plasma (ANA-PRP), Low-Level Laser Therapy (LLL-T), and Micro-Needling Technique (MN-T) used in combining for hair re-growth need to be standardized. Objectives: The work aims to show in vivo outcomes resulted from retrospective case-series study in which ANA-PRP + MN-T + LLL-T were used in combined in patients affected by Androgenic alopecia. Methods: 23 patients were treated, of which 13 males were classified in stage I - V by the Norwood–Hamilton scale, and 10 females were classified in stage I - III by the Ludwig scale. Assessment of hair re-growth was evaluated with photography, physician’s and patient’s global assessment scale, and standardized phototrichograms during a follow-up: T0 - baseline, T1 - 12 weeks, T2 - 23 weeks, T3 - 44 weeks, T4 - 58 weeks. Results: Interesting outcomes represented by a hair density increase of 81 ± 5 hairs/cm2 and 57 ± 7 hairs/cm2 respectively at T1 and T2 compared with baseline (173 ± 5 hairs/cm2 at T1 and 149 ± 9 hairs/cm2 at T2 versus 92 ± 2 hairs/cm2 at baseline) were observed using computerized trichograms. Conclusions: The effect of the combined use of MN-T, LLL-T, and ANA-PRP has been demonstrated.
Lingua originaleEnglish
pagine (da-a)1099-1109-1109
RivistaExpert Opinion on Biological Therapy
Volume20
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • Hair re-growth PRP
  • LLL-T therapy
  • Low-Level Laser therapy
  • regenerative plastic surgery
  • platelet-rich plasma
  • PRP
  • micro-needling

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